Can CBD Make You Nauseated? Pros, Cons, and Scientific Explanation

Can CBD Make You Nauseated?

Cannabidiol (CBD) is one of the many cannabis compounds and is gaining more recognition in the global health market. This non-intoxicating substance has shown potential for its therapeutic properties, such as reducing anxiety, inflammation, and pain. However, as with any substance, there may be side effects, and nausea is among them. This article will discuss the pros and cons of using CBD, how it affects the body, its potential to cause nausea and vomiting, and precautions to take to avoid these symptoms.

Pros and Cons of Using CBD

There are numerous benefits to using CBD, such as relief from anxiety, depression, and pain. CBD has been known to treat epileptic seizures, and research is underway to determine its effectiveness in treating cancer, multiple sclerosis, and Alzheimer’s. However, there are also side effects to be aware of when using CBD, such as fatigue, appetite changes, and diarrhea, to name a few. One side effect that has been reported is nausea, and it is important to understand how it affects the body before usage.

The Scientific Explanation

CBD contains receptors called CB1 and CB2, found in the central nervous system and peripheral tissues, respectively. CB1 has a high concentration in the brain and is responsible for the psychoactive effects of cannabis. In contrast, CB2 receptors are mainly found in body tissues and immune cells and contribute to the anti-inflammatory and pain-relieving benefits of cannabis. The mechanism of action of CBD is by interacting with the endocannabinoid system, which regulates various physiological processes. CBD inhibits the enzyme Fatty Acid Amide Hydrolase (FAAH), which increases the levels of endocannabinoids, resulting in reduced anxiety, inflammation, and pain. However, CBD can also interfere with the production of serotonin, which affects mood and may lead to nausea and vomiting.

Case Studies

Some people have reported experiencing nausea after taking CBD. An anonymous user on Reddit reported feeling nauseous after taking a CBD tincture, while another user on a forum experienced nausea after taking CBD gummies. The possible reasons for the adverse effects on the digestive system could be contributed to the quality of the product, the mode of administration, and the dosage.

Dosage and Preparation

The dosage and preparation of CBD products play a crucial role in its effect on the body. Some people who experience nausea after taking CBD may have overdosed or consumed CBD on an empty stomach. It is best to take CBD after food to avoid upsetting the stomach. Different products have different effects on the body. CBD oils and tinctures are absorbed faster and might cause a quicker onset of nausea, while CBD edibles may take longer to show an effect, but the symptoms may last longer. Therefore, it is essential to take CBD in moderation and start with small doses and gradually increase over time.

Cautions and Precautions

It is important to be cautious when taking CBD to avoid nausea and vomiting. One of the best ways to prevent nausea is to consume CBD after food. Likewise, it is advisable to drink plenty of water when using CBD, especially if you take it with other medications. If you experience nausea or vomiting after using CBD, it is best to stop using it immediately and speak with your doctor. CBD may interact with other medications and supplements, and it is best to have a personal consultation with your primary care provider.


CBD has been shown to have potential therapeutic benefits in the treatment of various conditions. However, it is vital to be mindful of the possible side effects that come with taking CBD. Nausea is among the side effects reported by some users, and it can be attributed to a variety of factors such as dosage and preparation. By being cautious, starting with low doses, and seeking professional advice, one can use CBD without experiencing side effects such as nausea. As always, one should check with their physician before taking any new supplements or medications.

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