Does CBD cancel the psychoactive effects of THC? This article explores the complex relationship between CBD and THC and explains the science behind their interactions. Learn about the entourage effect, how CBD and THC interact with the endocannabinoid system, and whether CBD can modify or negate THC’s effects. Discover the factors that influence how CBD affects THC and tips for balancing the psychoactivity of THC with the potential benefits of CBD.